What Is It?

Understanding Alpha-GPC

L-Alpha-Glycerylphosphorylcholine (Alpha-GPC) is a deacylated phosphatidylcholine derivative and natural compound that is widely used as a dietary supplement, especially, due to its crucial role in supporting cognitive function and overall brain health. Importantly, Alpha-GPC is a substance that could potentially augment human performance by facilitating neuromuscular interaction.

How It Works?

How Alpha-GPC Works?

Alpha‑GPC is a choline compound that easily crosses the blood–brain barrier to deliver choline right where your brain needs it. Once inside, it boosts production of acetylcholine—the neurotransmitter behind memory, learning, attention, and mental clarity. The result is sharper focus, quicker recall, and an overall lift in cognitive performance.

But Alpha‑GPC doesn’t stop at the brain. Because acetylcholine also drives muscle contractions, having more choline available means your nerves can fire stronger signals to your muscles. By feeding the acetylcholine system, Alpha‑GPC helps optimize the link between your nervous system and your muscles, potentially improving strength, power, and coordination during workouts.

Benefits

OVERALL TAKEAWAY

If you are looking to FOCUS UP and/or MUSCLE UP, then Alpha-GPC can give your brain and body the powerful boost they need to maximize the mind-muscle-movement connection and optimize your mental, athletic, muscular, and functional performance.

Every Day Impact of Alpha-GPC Supplementation and Science-Backed Results You Can Trust

Alpha‑GPC delivers a steady supply of choline to your brain, boosting acetylcholine levels and sharpening memory, attention, and mental clarity without the jittery side effects of stimulants. By enhancing the neurotransmitters that link your nervous system to your muscles, it deepens the mind‑muscle connection—resulting in faster reaction times, greater explosive power, and improved overall strength during lifting or sport‑specific drills.

At the same time, Alpha‑GPC naturally stimulates growth‑hormone release, helping your muscles recover more quickly and supporting long‑term gains in size and performance. Unlike caffeine, it won’t constrict blood vessels, raise heart rate, or dehydrate you, so you get clean, sustained energy for both body and mind.

Scientific research underpins these benefits. In 2015, Parker and colleagues showed that athletes taking Alpha‑GPC avoided the typical post‑exercise drop in choline, enjoyed longer endurance, and experienced a notable increase in growth‑hormone secretion. That same year, Bellar’s team reported significant gains in both upper‑body and lower‑body force output among strength athletes supplementing with Alpha‑GPC.

More recently, a 2021 study by Tamura and co‑researchers found that healthy adults who took Alpha‑GPC exhibited higher levels of motivation. Together, these findings confirm Alpha‑GPC as a powerful, science‑backed nootropic and pre‑workout ally for anyone looking to unite mental focus with physical performance.

Be KRE18 Elite, No Limits!

The KRE18 Elite Team and Community, all dedicated athletes, and demanding workouts and mental efforts require only the highest quality supplements to consistently maximize results, especially, long-term. The KRE18 Energy Booster ready-to-drink product includes a 300-milligram dose of Alpha-GPC, can be taken as a standalone focus- and/or performance-enhancement supplement whenever you may need it most, and would be the perfect addition to your current pre-workout supplementation stack.

Written By

Dr. Matt Gaston Villanueva, Ph.D.

Chief Scientific Officer, 

KRE18 Performance